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Obstetrics and Gynecology 1
Obstetrics and Gynecology 2

  • Koichiro Shimoya, M.D. Professor and Chairman
  • Takafumi Nakamura, M.D., Ph.D., Professor
  • Masahiko Nakata, M.D., Ph.D., Professor
INDEX :  Main Areas and Themes of Research    Clinical Features
       Educational Features

Main Areas and Themes of Research

Obstetrics and Gynecology is divided into four broad subspecialty categories. It consist of Perinatology (Maternal Fetal Medicine), Gynecologic Oncology, Reproductive Endocrinology & Infertility, and Urogynecology. Education in this field focuses on the diagnosis and treatment of each disease. Moreover, these four subspecialties contribute to lifelong progress concerning women’s quality of life in cooperation with other departments such as Basic Medicine, Neonatal Medicine, Pediatrics, Pathology, Urology, Surgery, Anesthesiology and Radiology.

It is our goal to support the life of women synthetically with Endocrinology, Oncology and Perinatology based on an excellent understanding of the reproduction system.

Our research is wide and various.
Related to Perinatology (Maternal Fetal Medicine):
  • Research concerning the pathophysiological analysis and prevention of abortion and preterm birth.
  • The analysis of neuroprotective factor in preeclampsia.
  • Research concerning oxidative stress and protease inhibitory substance in the uterine contraction.
  • Research on the stress answer response of the maternal body and the analysis of fetal programming
  • Research of fetal ultrasonograhy.
  • Clinical research regarding the obstetrics operation.
  • Clinical research on twin-twin transfusion syndrome.
Related to Reproductive Endocrinology & Infertility:
  • Research regarding the cytokine network in the female genital organs
  • Research concerning the influence of natural immunity in female genital organs
Related to Gynecologic Oncology:
  • Fundamental research about cancer generation using various knockout mice.
  • The genetic analysis of cancer generation.
  • Research regarding the efficacy of Chinese herbal medicine for cancer treatment.
Related to Urogynecology:
  • Research about the treatment of genital tract prolapse.
  • Research focusing on the relation between genital organ prolapse and nerve damage.
Recent activities:
  1. Secretory leukocyte protease inhibitor levels in cervicovaginal secretion of elderly women K Shimoya, et al. Maturitas. 2006 May 20 ; 54(2) : 141-8.
  2. Prospective study of nonclosure or closure of the peritoneum at cesarean delivery in 124 women: The impact of prior peritoneal closure at primary cesarean on the interval time between the first cesarean section and the next pregnancy and significant adhesion at the second cesarean Y Komoto, K Shimoya, et al. J Obstet Gynecol Res, 2006 Aug;32(4) : 396-402.
  3. Cesarean delivery after successful external cephalic version of breech presentation at term S. Matsuzaki, K. Shimoya, Y. Murata Int J Gynaecol Obstet. 2006 Jun;93(3) : 248-9
  4. S100B protein expression in the amnion and amniotic fluid in pregnancies complicated by pre-eclampsia. Tskitishvili E, Komoto Y, Temma-Asano K, Hayashi S, Kinugasa Y, Tsubouchi H, Song M, Kanagawa T, Shimoya K, Murata Y. Mol Hum Reprod. 2006 Dec ; 12(12) : 755-61
  5. Maternal positioning and fetal positioning in utero. Matsuo K, Shimoya K, Ushioda N, Kimura T. J Obstet Gynaecol Res. 2007 Jun ; 33(3) : 279-82.
  6. Level of S100B protein expression in the amnion at various gestational ages in the third trimester of normal pregnancies. Tskitishvili E, Komoto Y, Kinugasa Y, Kanagawa T, Song M, Mimura K, Tomimatsu T, Kimura T, Shimoya K. Acta Obstet Gynecol Scand. 2007 ; 86(8) : 915-20.
  7. Relationship Between Human Tumor-Associated Antigen RCAS1 and Gestational Diabetes Mellitus. Tskitishvili E, Komoto Y, Kinugasa Y, Kanagawa T, Song M, Mimura K, Tomimatsu T, Kimura T, Shimoya K. Am J Reprod Immunol. 2007 Nov ; 58(5) : 440-6.
  8. Is 38 weeks late enough for elective cesarean delivery?Matsuo K, Komoto Y, Kimura T, Shimoya K Int J Gynaecol Obstet. 2007 Aug 27 ;[Epub ahead of print]
  9. Combination chemotherapy of intraperitoneal carboplatin and intravenous paclitaxel in suboptimally debulked epithelial ovarian cancer. Int J Gynecol Cancer. 2008 Feb 15.[Epub ahead of print]Nagao S, Fujiwara K, Ohishi R, Nakanishi Y, Iwasa N, Shimizu M, Goto T, Shimoya K.
  10. Maternal urinoma during pregnancy. J Obstet Gynaecol Res. 2008 Feb ; 34(1): 88-91. Review. Ushioda N, Matsuo K, Nagamatsu M, Kimura T, Shimoya K.

Clinical Features

The Department of Obstetrics and Gynecology focuses its clinical activity on obstetrics, and routine well-known gynecologic services which include advanced gynecologic surgery such as minimally invasive operative procedures and cancer surgeries. It also incorporates aspects concerning sexual health, family planning, menopause, and reproductive education. We have almost 40 years experience of excellence in women’s health and the highest level of quality patient care. We provide one of the best medical services in the Okayama area.

Educational Features

Block Lectures:

We give a 68-hour block lecture which is called "women’s reproduction" for 4th grade medical students. It concerns the physiology and pathology of a fetus, the newborn baby, mammary glands and radiology, in addition to reproductive medicine which is the basis of a study of obstetrics and gynecology, and we try to cover indispensable items widely to include boundary and related areas as well. Our students learn fundamental knowledge regarding the study of obstetrics, gynecology and reproductive medical science, and are prepared for essential activities such as clinical training in the hospital for the following year and a national examination.

Clinical training:

The clinical training of obstetrics and gynecology is held for 5th grade medical students. It is held every two weeks with rotation of 1 group (4-6 people). The faculty in the Department of Obstetrics and Gynecology is responsible for the direct supervision and teaching of resident physicians and medical students in clinical settings (including outpatient clinic, operation room, inpatient ward) at the Kawasaki Medical School Hospital. Faculty members also participate in community lectures and Grand Rounds presentations on a variety of topics.