HOME >>  Research - Introduction of Departments - Pathology 2

Pathology 2

  • Takuya Moriya, M.D., Ph.D. Professor

Emphasis and Outline of Education

The pathology department includes a two-course system with Pathology 1. Both departments cooperate and oversee undergraduate and postgraduate education. An introduction to pathology is provided in the second school year in the last stage of education on basic medicine, and focuses on the specific nature of disease for the first time. The course complements other subjects and acquaints students with complex concepts of disease in order to advance their learning and enhance their clinical knowledge in a progressive manner. The practical content shifts from use of the microscope to the virtual slide using a personal computer in an effort to effectively educate students. Lectures concern physiology, and an itemized discussion of conventional pathology is integrated into the block of lectures in the 3rd-4th school year, with a comparison between the practical value of diagnostic imaging and macro pathology. It is important that the clinical training in the end of 4th school year provides students with experience of the importance of so-called clinical pathology and diagnosis pathology, where pathology is seen in the context of the hospital and clinical medicine. The importance of the correlation with human pathology is an important matter that students learn using concrete examples. When becoming doctors in a variety of specialized diagnosis and treatment departments in the future, we want them to appreciate the value of pathology in their chosen field. Furthermore, we hope the some students become pathology specialists.

Main Areas and Themes of Research

Our research aims to develop basic aspects of anatomic/surgical pathology. We also aim for more positive cooperation with other departments and organizations outside the school. Our technological and research findings aim to assist areas concerning internal organs and disease, breast disorders, gynecological tumors, and urological tumors.

Main ongoing topics of research:
  1. Examination of the pathologic histology evaluation method for individualization treatment of breast cancer: They include immunohistochemical findings of early breast cancer and its precursor, clinicopathological study that aims to clarify adjustment of a new treatment to triple negative breast cancer, characteristic features of lectin histochemisty for various type of breast carcinomas, and hormone environment evaluation of male breast cancers (some are joint researches with other facilities).
  2. Clinicopathologic features and the mechanism of invasive micropapillary carcinoma of the breast.
  3. Pathology examination concerning features of diagnosis accuracy of gynecologic tumors (uterine cervix, endometrium and ovary)
  4. A clinicopathological analysis of the significance of blood vessel proliferation inhibitor in various tumors (joint research with other facilities)
  5. A basic and pathologic histology examination concerning the selection of chemotherapy of urologic carcinomas (regarding chemotherapeutic drugs mainly in relation to blood vessel proliferation control).
The Ministry of Health, Labour and Welfare research group (2013 fiscal year: Group leader cooperator):

(A) Clinicopathologic significance and morphological approach for the early stage invasive breast carcinomas. (2013-2015)

(B) Analysis of the mechanism of metastasis for invasive micropapillary carcinoma of the breast. (2013-2015)

Joint research / Collaborative study:

(C) The chief investigator of the research group of the Japanese Society of breast Cancer: significance of Ki-67 proliferation index in luminal type breast carcinoma (2012-2014)

(D) The chief investigator of the research group of the Japanese Society of Clinical Cytology: The retrospective review of the accuracy of automated screening for the pap smear of uterine cervical cytology. (2013-2014)

(E) Collaborator, National Cancer Center Research and Development Fund, The Clinical support for the development of the accuracy of cancer medicine and its quality control. (2011-2014)

(F) A clinicopathological analysis of the significance of blood vessel proliferation inhibitor in gatstrointestinal stromal tumor (joint research with other facilities) (2013)

Clinical Features

Our lecture belongs to a section of clinical medicine and helps educate medical students about clinicopathology through a positive cooperation with the hospital.

Educational Features

Another feature of this classroom is its strong connection with the contemporary medical museum (Medical Museum: MM). The MM has unparalleled facilities and almost all of the exhibits represent current advances in medicine. The exhibits of the third floor comprise a stock of more than 4,000 gross internal organs and 17 exhibitions of pathology CPC that form a significant aspect of our department. We use these resources for teaching purposes. In addition, we want to engage in an initial clinical training and to work on creating various self-moving models.

English homepage of Kawasaki Medical Museum;

We aim to support our staff pathologists because we are a comparatively young department, and hope to develop an environment that encourages research, especially for postgraduates. Participation in joint research is one of our goals. We stand in a mid-term position for the MM and keep in mind the need to update the exhibits.