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Laborotory Animal Management Research Center

  • Manager:Seitaro Okuma, M.D., Ph.D. (Professor of Pharmacology)
  • Sub-manager:Tetsuya Okino, Ph.D. (Assistant Professor of Microbiology)

Outline of Laborotory Animal Management Research Center

The Laboratory Animal Management Research Center (LAC) is a rearing facility of laboratory animals essential for medical and biological research. LAC aims to reduce the financial and labor load on researchers by maintaining laboratory animals and enhancing the accuracy and reliability of experimental results that rely on their use.

LAC comprises five areas:

1) Conventional,2) Clean,3) SPF (Specific Pathogen Free),4) Infectious diseases (10F, except for large animals), and 5) Administration areas.

Each area possesses a different microbiological standards grade. The air-conditioning system within LAC is independent of other facilities, and every animal can be maintained under an appropriate environment throughout the year.

The aforementioned five areas are for common use by researchers (except for subdivision) and the laboratory animals used in experiments approved by the Animal Experiment Committee of Kawasaki Medical School are under the control of each area (except for animals used in radioisotope experiments).

The maintenance of genetically modified animals, disease-model animals or animals in need of special management is the responsibility of the researchers themselves. As the SPF area is a specific pathogen-free environment, researchers can perform animal experiments with high reproducibility, reliability and accuracy.

Operation of LAC is based on guidelines outlined in The Use Regulations of Laboratory Animal Management Research Center. The operating policy is defined according to current developments in medical studies and specific needs of the researchers using our facilities. The LAC committee carefully considers the short- and long-term operating requirements of each researcher.

Prior to the commencement of any animal experiments, researchers should submit an animal experiment protocol to the Animal Experiment Committee of Kawasaki Medical School and apply for registration with LAC. Following the granting of permission by the Committee and successful registration with LAC, researchers are permitted to transport animals to the facilities and begin their experimental work. Researchers are expected to pay a part of the expenses for supplies and the cost involved for animal breeding. In accordance with the aforementioned regulation guidelines, a request by researchers to utilize LAC facilities is required, and all requests are treated on an equal basis regardless of the applicant’s position. Every effort is made by LAC to accommodate the special needs of the researcher.

Within LAC, the rearing and maintenance of laboratory animals are performed with the following considerations:

1) Animals reared in our facilities are of excellent quality. 2) The environment for the rearing of animals is kept clean and complies with the institutional standard concerning pathogens. 3) Animal protection and welfare are kept in mind at all times.

LAC is committed to maintaining an environment for the management of laboratory animals according to the humane protection of laboratory animals.