週刊医学のあゆみ 2018 267(10):741-745.

Naito T, Yasunaga JI, Mitobe Y, Shirai K, Sejima H, Ushirogawa H, Tanaka Y, Nakamura T, Hanada K, Fujii M, Matsuoka M,
Saito M.
Distinct gene expression signatures induced by viral transactivators of different HTLV-1 subgroups that confer a different risk of HAM/TSP.
Retrovirology. 2018 Nov 6;15(1):72. doi: 10.1186/s12977-018-0454-x.

齊藤明子、齊藤峰輝、下江 豊、吉本武史、川上万里、岡本宏明、吉川恵輔、楠 進、栗山 勝
臨床神経学 2018 58:574-577.

Sakai T, Takagi H, Muraki Y, Saito M.Unique directional motility of influenza C virus controlled by its filamentous morphology and short-range motions.
Journal of Virology. 2018 Jan 2;92(2). pii: e01522-17. doi: 10.1128/JVI.01522-17.


Saito M, Sejima H, Naito T, Ushirogawa H, Matsuzaki T, Matsuura E, Tanaka Y, Nakamura T, Takashima H.
The CC chemokine ligand (CCL) 1, upregulated by the viral transactivator Tax, can be downregulated by minocycline: possible implications for long-term treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis.
Virology Journal. 2017 14(1):234. doi: 10.1186/s12985-017-0902-6.

Sakihama S, Saito M, Kuba-Miyara M, Tomoyose T, Taira N, Miyagi T, Hayashi M, Kinjo S, Nakachi S, Tedokon I, Nishi Y, Tamaki K, Morichika K, Uchihara J, Morishima S, Karube K, Tanaka Y, Masuzaki H, Fukushima T.
Human T-cell Leukemia Virus Type I Tax genotype analysis in Okinawa, the southernmost and remotest islands of Japan: Different distributions compared with mainland Japan, and the potential value for the prognosis of aggressive adult T-cell leukemia/lymphoma.
Leukemia Research. 2017 Oct;61:18-24. doi: 10.1016/j.leukres.2017.08.006.

Shiohama Y, Naito T, Matsuzaki T, Tanaka R, Tomoyose T, Takashima H, Fukushima T, Tanaka Y, Saito M.
Prevalence of plasma autoantibody against cancer testis antigen NY-ESO-1 in HTLV-1 infected individuals with different clinical status.
Virology Journal.2017 14(1):130.

Ujimine S, Tone S, Saito M, Yamada S.
Intracellular morphological changes in Staphylococcus aureus induced by treatment with sodium hypochlorite.
Medical Molecular Morphology. 2017 May 17. doi: 10.1007/s00795-017-0159-6.

Sakai T, Nishimura SI, Naito T, Saito M.
Influenza A virus hemagglutinin and neuraminidase act as novel motile machinery.
Scientific Reports. 2017 7: Article number: 45043. doi:10.1038/srep45043.

Saito M.
Reference Module in Life Sciences. 2017

Okino T, Ushirogawa H, Matoba K, Nishimatsu S, Saito M.
Establishment of the complete life cycle of Spirometra (Cestoda: Diphyllobothriidae) in the laboratory using a newly isolated triploid clone.
Parasitology International. 2017 66(2):116-118.

Naito T, Mori K, Ushirogawa H, Takizawa N, Nobusawa E, Odagiri T, Tashiro M, Ohniwa RL, Nagata K, Saito M.
Generation of a genetically stable high-fidelity influenza vaccine strain.
Journal of Virology. 2017 91(6):pii: e01073-16. doi: 10.1128/JVI.01073-16.

Nagano T, Katase M, Tsumura K, Saito M, Matsuda T.
Inhibitory effects of dietary soyasaponin on 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice.
Experimental Dermatology. 2017 26(3):249-254. doi: 10.1111/exd.13205.


Ushirogawa H, Naito T, Tokunaga H, Tanaka T, Nakano T, Terada K, Ohuchi M, Saito M.
Re-emergence of H3N2 strains carrying potential neutralizing mutations at the N-linked glycosylation site at the hemagglutinin head, post the 2009 H1N1 pandemic.
BMC Infectious Diseases. 2016 16:380. doi: 10.1186/s12879-016-1738-1.

Shiohama Y, Naito T, Matsuzaki T, Tanaka R, Tomoyose T, Takashima H, Fukushima T, Tanaka Y, Saito M.
Absolute quantification of HTLV-1 basic leucine zipper factor (HBZ) protein and its plasma antibody in HTLV-1 infected individuals with different clinical status.
Retrovirology. 2016 13:29. doi: 10.1186/s12977-016-0263-z.

病原微生物に対する免疫とワクチン I. 免疫を知るー神経免疫学の基礎(分担執筆)p52-56.
免疫性神経疾患-病態と治療のすべて アクチュアル 脳・神経疾患の臨床
専門編集:吉良潤一(九州大学) 総編集:辻 省次(東京大学) 中山書店

Yasuma K, Matsuzaki T, Yamano Y, Takashima H, Matsuoka M, Saito M.
HTLV-1 subgroups associated with the risk of HAM/TSP are related to viral and host gene expression in peripheral blood mononuclear cells, independent of the transactivation functions of the viral factors.
Journal of Neurovirology. 2016 22(4):416-30. doi: 10.1007/s13365-015-0407-2. Epub 2015 Dec 3.

Nakamura K, Shirakura M, Suzuki Y, Naito T, Fujisaki S, Tashiro M, Nobusawa E.
Development of a high-yield reassortant influenza vaccine virus derived from the A/Anhui/1/2013 (H7N9) strain.
Vaccine. 2016 34(3):328-33. doi: 10.1016/j.vaccine.2015.11.050. Epub 2015 Dec 1.


高宮資宜、高松和弘、下江 豊、齊藤峰輝、栗山 勝
神経内科 2015 83(1):74-79.

兵 行義、石松昌己、河口 豊、山田作夫、齊藤峰輝原田 保
日本耳鼻咽喉科感染症・エアロゾル学会会誌 2015 3(1):28-32.


Saito M, Tanaka R, Fujii H, Kodama A, Takahashi Y, Matsuzaki T, Takashima H, Tanaka Y.
The neutralizing function of the anti-HTLV-1 antibody is essential in preventing in vivo transmission of HTLV-1 to human T cells in NOD-SCID/γcnull (NOG) mice.
Retrovirology. 2014 Aug 28;11(1):74.

Tanaka Y, Takahashi Y, Tanaka R, Kodama A, Fujii H, Hasegawa A, Kannagi M, Ansari AA, Saito M.
Elimination of human T cell leukemia virus type-1-infected cells by neutralizing and antibody-dependent cellular cytotoxicity-inducing antibodies against human t cell leukemia virus type-1 envelope gp46.
AIDS Research and Human Retroviruses. 2014 Jun;30(6):542-52. doi: 10.1089/AID.2013.0214.

Saito M.
Neuroimmunological aspects of human T cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis.
Journal of Neurovirology. 2014 Apr;20(2):164-74. doi: 10.1007/s13365-013-0192-8.

Saito M.
Pathogenic conversion of forkhead box protein 3-positive T cells into T helper 17 cells: Is this also the case for multiple sclerosis?
Clinical and Experimental Neuroimmunology. 2014 Jun 26; 5(2): 112–3. doi: 10.1111/cen3.12114.

Fukuishi N, Murakami S, Ohno A, Yamanaka N, Matsui N, Fukutsuji K, Yamada S, Itoh K, Akagi M.
Does β-hexosaminidase function only as a degranulation indicator in mast cells? The primary role of β-hexosaminidase in mast cell granules.
Journal of Immunology. 2014 Aug 15;193(4):1886-94. doi: 10.4049/jimmunol.1302520.

Oshiro Y, Yasue H, Takahashi K, Hattori S, Ideno S, Urayama T, Chiba M, Osari S, Naito T, Takeuchi K, Nagata K, Ohkohchi N. Mode of swine hepatitis E virus infection and replication in primary human hepatocytes.
Journal of General Virology. 2014 Dec;95(Pt 12):2677-82. doi: 10.1099/vir.0.068452-0.

Ryno LM, Genereux JC, Naito T, Morimoto RI, Powers ET, Shoulders MD, Wiseman RL.
Characterizing the altered cellular proteome induced by the stress-independent activation of heat shock factor 1.
ACS Chemical Biology. 2014 Jun 20;9(6):1273-83. doi: 10.1021/cb500062n.

Shiohama Y, Ohtake J, Ohkuri T, Noguchi D, Togashi Y, Kitamura H, Nishimura T.
Identification of a meiosis-specific protein, MEIOB, as a novel cancer/testis antigen and its augmented expression in demethylated cancer cells.
Immunology Letters. 2014 Mar-Apr;158(1-2):175-82. doi: 10.1016/j.imlet.2014.01.004.


Saito M, Tanaka R, Arishima S, Matsuzaki T, Ishihara S, Tokashiki T, Ohya Y, Takashima H, Umehara F, Izumo S, Tanaka Y.
Increased expression of OX40 is associated with progressive disease in patients with HTLV-1- associated myelopathy/tropical spastic paraparesis.
Retrovirology. 2013 May 7;10:51. doi: 10.1186/1742-4690-10-51.

Kodama A, Tanaka R, Saito M, Ansari AA, Tanaka Y.
A novel and simple method for generation of human dendritic cells from unfractionated peripheral blood mononuclear cells within 2 days: its application for induction of HIV-1-reactive CD4(+) T cells in the hu-PBL SCID mice.
Frontiers in Microbiology. 2013 Sep 27;4:292. doi: 10.3389/fmicb.2013.00292.

Saito M.
Stanley Maloy, Kelly Hughes ed.
Encyclopedia of Genetics 2nd Edition, Elsevier, Oxford, UK. 2013:543-5.

Hyo Y, Yamada S, Fukutsuji K, Harada T.
Thickening of the cell wall in macrolide-resistant Staphylococcus aureus.
Medical Molecular Morphology. 2013 Dec;46(4):217-24. doi: 10.1007/s00795-013-0027-y. Epub 2013 Feb 14.

Shimotahira N, Oogai Y, Kawada-Matsuo M, Yamada S, Fukutsuji K, Nagano K, Yoshimura F, Noguchi K, Komatsuzawa H.
The surface layer of Tannerella forsythia contributes to serum resistance and oral bacterial coaggregation.
Infection and Immunity. 2013 Apr;81(4):1198-206. doi: 10.1128/IAI.00983-12.

Fukutsuji K, Yamada S, Harada T.
Ultrastructural cell wall characteristics of clinical gentamycin-resistant Staphylococcus aureus isolates.
Medical Molecular Morphology. 2013 Jun;46(2):70-6. doi: 10.1007/s00795-013-0009-0.

沖野哲也、後川潤、的場久美子、齊藤峰輝、森 生枝
岡山県自然保護センターで捕獲された外来齧歯類ヌートリアMyocastor coypusの寄生虫調査
岡山県自然保護センター研究報告 2013 (20):1-6.


Saito M, Bangham CR.
Immunopathogenesis of human T-cell leukemia virus type-1-associated myelopathy/tropical spastic paraparesis: recent perspectives.
Leukemia Research and Treatment. 2012;2012:259045. doi: 10.1155/2012/259045.

Saito M, Jain P, Tsukasaki K, Bangham CR.
HTLV-1 Infection and Its Associated Diseases.
Leukemia Research and Treatment. 2012;2012:123637. doi: 10.1155/2012/123637.

Hyo Y, Yamada S, Ishimatsu M, Fukutsuji K, Harada T.
Antimicrobial effects of Burow's solution on Staphylococcus aureus and Pseudomonas aeruginosa.
Medical Molecular Morphology. 2012 Jun;45(2):66-71. doi: 10.1007/s00795-011-0540-9.

Kawada-Matsuo M, Mazda Y, Oogai Y, Kajiya M, Kawai T, Yamada S, Miyawaki S, Oho T, Komatsuzawa H.
GlmS and NagB regulate amino sugar metabolism in opposing directions and affect Streptococcus mutans virulence.
PLoS One. 2012;7(3):e33382. doi: 10.1371/journal.pone.0033382.

Kobayashi M, Ashino S, Shiohama Y,Wakita D, Kitamura H, Nishimura T.
IFN-γ elevates airway hyper-responsiveness via up-regulation of neurokinin A/neurokinin-2 receptor signaling in a severe asthma model.
European Journal of Immunology. 2012 Feb;42(2):393-402. doi: 10.1002/eji.201141845.

標準微生物学第11版, 75-84, 医学書院, 2012.

沖野哲也、後川潤、的場久美子、初鹿 了
川崎医学会誌 2012 38(3):143-150.

春間 賢、石井 学、村尾高久、鎌田智有、塩谷昭子、眞部紀明、山下直人、後川潤、沖野哲也
第14回 経鼻内視鏡で虫体を摘出した胃アニキサス症の1例
The GI Forefront 2012 7(2):91-93.

肥田浩亮、石井 学、垂水研一、沖野哲也、鎌田智有、松本啓志、佐藤元紀、村尾高久、中津川善和、木村佳起、大澤元保、本多啓介、塩谷昭子、 畠 二郎、春間 賢
消化管の臨床 2012 17:81-84.


Adachi T, Tanaka R, Kodama A, Saito M, Takahashi Y, Ansari AA, Tanaka Y.
Identification of an unique CXCR4 epitope whose ligation inhibits infection by both CXCR4 and CCR5 tropic human immunodeficiency type-I viruses.
Retrovirology. 2011 Oct 22;8:84. doi: 10.1186/1742-4690-8-84.

Ushirogawa H, Ohuchi M.
Novel antiviral activity of neuraminidase inhibitors against an avian influenza a virus.
Virology Journal. 2011 Aug 19;8:411. doi: 10.1186/1743-422X-8-411.

Tokunaga H, Ushirogawa H, Ohuchi M.
The pandemic (H1N1) 2009 influenza virus is resistant to mannose-binding lectin.
Virology Journal. 2011 Feb 4;8:50. doi: 10.1186/1743-422X-8-50.

Numajiri Haruki A, Naito T, Nishie T, Saito S, Nagata K.
Interferon-inducible antiviral protein MxA enhances cell death triggered by endoplasmic reticulum stress.
Journal of Interferon & Cytokine Research. 2011 Nov;31(11):847-56. doi: 10.1089/jir.2010.0132.

シンプル微生物学第5版, 13-20, 南江堂, 2011.

川崎医療福祉学会誌, 20(2): 405-410, 2011/03.

川崎医療福祉学会誌, 20(2): 379-404, 2011/03.

井上真理子、三上崇徳、小郷 哲、沖野哲也、大熊誠太郎
岡山実験動物研究会報 2011 27:8-11.


Okuwa T, Taniura N, Saito M, Himeda T, Ohara Y.
Opposite effects of two nonstructural proteins of Theiler’s murine encephalomyelitis virus regulates apoptotic cell death in BHK-21 cells.
Microbiology and Immunology. 2010 Oct;54(10):639-43. doi: 10.1111/j.1348-0421.2010.00260.x.

Tanaka R, Takahashi Y, Kodama A, Saito M, Ansari AA, Tanaka Y.
Suppression of CCR5-tropic HIV type 1 infection by OX40 stimulation via enhanced production of β-chemokines.
AIDS Research and Human Retroviruses. 2010 Oct;26(10):1147-54. doi: 10.1089/aid.2010.0043.

Saito K, Saito M,Taniura N, Okuwa T, Ohara Y.
Activation of the PI3K-Akt pathway by human T cell leukemia virus type 1 (HTLV-1) oncoprotein Tax increases Bcl3 expression, which is associated with enhanced growth of HTLV-1-infected T cells.
Virology. 2010 Aug 1;403(2):173-80. doi: 10.1016/j.virol.2010.04.018.

Kodama A, Tanaka R, Zhang LF, Adachi T, Saito M, Ansari AA, Tanaka Y.
Impairment of in vitro generation of monocyte-derived human dendritic cells by inactivated human immunodeficiency virus-1: Involvement of type I interferon produced from plasmacytoid dendritc cells.
Human Immunology. 2010 Jun;71(6):541-50. doi: 10.1016/j.humimm.2010.02.020.

Saito M.
Immunogenetics and the Pathological Mechanisms of Human T-Cell Leukemia VirusType 1- (HTLV-1-)Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).
Interdisciplinary Perspectives on Infectious Diseases. 2010;2010:478461. doi: 10.1155/2010/478461.

Ashino S, Wakita D, Shiohama Y,Iwakura Y, Chamoto K, Ohkuri T, Kitamura H, Nishimura T.
A T(h)17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-{gamma} production in order to induce airway hyperresponsiveness.
International Immunology. 2010 Jun;22(6):503-13. doi: 10.1093/intimm/dxq034.

血液・腫瘍科60: 642-650, 2010.

兵 行義、山田作夫、 原田保
顕微鏡 45(4): 218-222, 2010.

沖野哲也、後川 潤、的場久美子、初鹿 了
川崎医学会誌 2010 36(2):127-141.

沖野哲也、後川 潤、的場久美子、初鹿 了
川崎医学会誌 2010 36(2):121-126.

沖野哲也、後川 潤、的場久美子、初鹿 了
川崎医学会誌 2010 36(2):115-120.

臨床皮膚科 2010 64(13):1069-1072.


Taniura N, Saito M, Okuwa T, Saito K, Ohara Y.
Different subcellular localization of Theiler's murine encephalomyelitis virus leader proteins of GDVII and DA strains in BHK-21 cells.
Journal of Virology. 2009 Jul;83(13):6624-30. doi: 10.1128/JVI.02385-08.

Saito M, Matsuzaki T, Satou Y, Yasunaga J, Saito K, Arimura K, Matsuoka M, Ohara Y.
In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Retrovirology. 2009 Feb 19;6:19. doi: 10.1186/1742-4690-6-19.

Sabouri AH, Usuku K, Hayashi D, Izumo S, Ohara Y, Osame M, Saito M.
Impaired function of human T-lymphotropic virus type 1 (HTLV-1)-specific CD8+ T cells in HTLV-1-associated neurologic disease.
Blood. 2008 Sep 15;112(6):2411-20. doi: 10.1182/blood-2008-02-140335.

Nose H, Kubota R, Seth N, Goon P, Tanaka Y, Izumo S, Usuku K, Ohara Y, Wucherpfennig K, Bangham C, Osame M, Saito M.
Ex vivo analysis of human T lymphotropic virus type 1-specific CD4+ cells by use of a major histocompatibility complex class II tetramer composed of a neurological disease-susceptibility allele and its immunodominant peptide.
Journal of Infectious Diseases. 2007 Dec 15;196(12):1761-72. doi: 10.1086/522966.

Saito M, Braud VM, Goon P, Hanon E, Taylor GP, Saito A, Eiraku N, Tanaka Y, Usuku K, Weber JN, Osame M, Bangham CR.
Low frequency of CD94/NKG2A+ T lymphocytes in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis, but not in asymptomatic carriers.
Blood. 2003 Jul 15;102(2):577-84.

Saito M, Taylor GP, Saito A, Furukawa Y, Usuku K, Weber JN, Osame M, Bangham CR. In vivo selection of T-cell receptor junctional region sequences by HLA-A2 human T-cell lymphotropic virus type 1 Tax11-19 peptide complexes.
Journal of Virology. 2001 Jan;75(2):1065-71.

Hanon E, Stinchcombe JC, Saito M,Asquith BE, Taylor GP, Tanaka Y, Weber JN, Griffiths GM, Bangham CR.
Fratricide among CD8(+) T lymphocytes naturally infected with human T cell lymphotropic virus type I.
Immunity. 2000 Nov;13(5):657-64.

Kawai M, Yamada S, Ishidoshiro A, Oyamada Y, Ito H, Yamagishi J.
Cell-wall thickness: possible mechanism of acriflavine resistance in meticillin-resistant Staphylococcus aureus.
Journal of Medical Microbiology. 2009 Mar;58(Pt 3):331-6. doi: 10.1099/jmm.0.004184-0.

Oku Y, Kurokawa K, Matsuo M, Yamada S, Lee BL, Sekimizu K.
Pleiotropic roles of polyglycerolphosphate synthase of lipoteichoic acid in growth of Staphylococcus aureus cells.
Journal of Bacteriology. 2009 Jan;191(1):141-51. doi: 10.1128/JB.01221-08.

Yamada S, Hyo Y, Ohmori S, Ohuchi M.
Role of ciprofloxacin in its synergistic effect with fosfomycin on drug-resistant strains of Pseudomonas aeruginosa.
Chemotherapy. 2007;53(3):202-9.

Ohyama F, Ushirogawa H, Furukawa N, Matoba K, Okino T.
Growth and development of Massaliatrema misgurni (Trematoda: Heterophyidae) in mice and its metacercarial morphology.
Parasitology International. 2004 Dec;53(4):301-6.

Fujita M, Koga H, Iida M, Hirakawa K, Hoshika K, Haruma K, Okino T.
The diagnostic yield of colonoscopy and the therapeutic value of intraduodenal amidotrizoic acid injection in intestinal Diphyllobothrium latum infection: report of a case.
American Journal of Gastroenterology. 2002 Sep;97(9):2468-70.

Koga M, Ushirogawa H, Tomioka K.
Photoperiodic modulation of circadian rhythms in the cricket Gryllus bimaculatus.
Journal of Insect Physiology. 2005 Jun;51(6):681-90.

Ohuchi M, Asaoka N, Sakai T,Ohuchi R.
Roles of neuraminidase in the initial stage of influenza virus infection.
Microbes and Infection. 2006 Apr;8(5):1287-93. Epub 2006 Feb 8.

Sakai T, Ohuchi M, Imai M, Mizuno T, Kawasaki K, Kuroda K, Yamashina S.
Dual wavelength imaging allows analysis of membrane fusion of influenza virus inside cells.
Journal of Virology. 2006 Feb;80(4):2013-8.

Asaoka N, Tanaka Y, Sakai T,Fujii Y, Ohuchi R, Ohuchi M.
Low growth ability of recent influenza clinical isolates in MDCK cells is due to their low receptor binding affinities.
Microbes and Infection. 2006 Feb;8(2):511-9. Epub 2005 Oct 18.

Nagata K, Kawaguchi A, Naito T.
Host factors for replication and transcription of the influenza virus genome.
Reviews in Medical Virology.2008 Jul-Aug;18(4):247-60. doi: 10.1002/rmv.575. Review.

Naito T, Kiyasu Y, Sugiyama K, Kimura A, Nakano R, Matsukage A, Nagata K.
An influenza virus replicon system in yeast identified Tat-SF1 as a stimulatory host factor for viral RNA synthesis.
Proc. Natl. Acad. Sci. USA. 2007 Nov 13;104(46):18235-40.

Naito T, Momose F, Kawaguchi A, Nagata K.
Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits.
Journal of Virology. 2007 Feb;81(3):1339-49.

Kawaguchi A, Naito T, Nagata K.
Involvement of influenza virus PA subunit in assembly of functional RNA polymerase complexes.
Journal of Virology. 2005 Jan;79(2):732-44.

Momose F, Naito T, Yano K, Sugimoto S, Morikawa Y, Nagata K.
Identification of Hsp90 as a stimulatory host factor involved in influenza virus RNA synthesis.
Journal of Biological Chemistry. 2002 Nov 22;277(47):45306-14.